Cardiac Remodelling

Assessment of Cardiac Remodelling

Ventricular-aortic coupling as a marker of stenting efficacy: Aortic coarctation results in left ventricular hypertrophy and hypertension. Despite a surgical resection of the coarctation segment without residual aortic arch obstruction, many patients are still hypertensive and left ventricular hypertrophy persists. As a long-term validation, clinicians will be examining ventriculo-aortic coupling modelling aortic valve and proximal aortic function, left ventricular mechanics coupled with flow to predict an optimal therapeutic outcome. It is hypothesized that a failure to reverse ventricular hypertrophy and strain post stenting is a prognostic marker of a poor near term (2 years) hemodynamic outcome.